NOVEL THERAPY FOR PANCREATIC CANCERS, TARGETING MOLECULAR FOUNDATION
Dr Michael KC Lee,
Medical Oncologist,
Peter MacCallum Cancer Centre,
Melbourne, Australia
RESEARCHER PROFILE
Filmed in Melbourne, Australia | February 2026
Dr Michael Lee is an experienced medical oncologist, sub-specialising in gastrointestinal cancers and neuroendocrine tumours at the Peter MacCallum Cancer Centre.
He plays a key role in molecular tumour boards at VCCC Alliance (Victorian Comprehensive Cancer Centre) and MPCCC (Monash Partners Comprehensive Cancer Consortium), ensuring the accurate and effective use of precision medicine in cancer care across the state.
His care philosophy, embodied in his practice name, “Can-Therapy,” promotes a CAN-do approach to CANcer care: empowering patients to thrive beyond cancer through cutting-edge research and personalised, values-driven care. Beyond the clinic, he leads research as a clinician scientist, developing therapeutic strategies that target RNA processing – the molecular blueprint cancer hijacks to fuel its growth and resistance – by altering its sequence is like changing words in a sentence to redefine cancer’s trajectory.
Supported by Pancare Foundation, the Paul Dear Post Doctoral Fellowship and his industry collaboration, his work aims to revolutionise outcomes for patients with this aggressive cancer by targeting its molecular foundation.
He is a recognised expert in pancreatic cancer care, combining research insights with exceptional patient care, while also providing comprehensive treatment for all cancer types.
Source: Supplied
https://orcid.org/0000-0001-8075-3608
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Targeting chemotherapy resistance in ovarian cancer patients
Dr Alex Cole, from the Centenary Institute’s Centre for Biomedical AI, is now leading the research focused on developing a new treatment to counteract a protein called follistatin (FST), known for making ovarian cancer cells resistant to chemotherapy.
By employing cutting-edge molecular biology and directed evolution techniques, the project aims to create nanobodies—small, precise molecules—that can block FST. If successful, these nanobodies could enhance the effectiveness of chemotherapy and improve ovarian cancer treatment rates.
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Risk factors and prevention of respiratory infections and infectious diseases in children
A/Prof Hannah Moore OAM is an infectious disease epidemiologist; Co-Head of the Infectious Disease Epidemiology team within the Wesfarmers Centre of Vaccines and Infectious Diseases at The Kids Research Institute Australia and Associate Professor at the School of Population Health, Curtin University in Western Australia.
A/Prof Moore has been awarded more than $19M in competitive research grants, co-authored more than 140 papers, was TEDxPerth 2018 speaker, recipient of a WA Young Tall Poppy Award (2013) and the WA Premiers Science Early Career Scientist Award (2015). In 2024, she was honoured with a Medal of the Order of Australia for her service to epidemiology as a researcher.
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At the frontier of human cellular neuroscience research
Associate Professor Cedric Bardy is the Director of The Laboratory for Human Neurophysiology, Genetics & Stem Cells, located at SAHMRI. South Australia.
His current research uses preclinical, patient-derived cell models to test innovative therapeutic strategies, with a current focus on Parkinson’s disease, brain cancer and childhood dementia (Sanfilippo syndrome).
His work has established a platform to facilitate the discovery and validation of treatments for brain disorders. Their research is at the frontier of human cellular neuroscience research and translational applications that benefit global public health.
