BRAIN AGEING, DEMENTIA AND PSYCHIATRIC DISORDERS
Professor Perminder S. Sachdev AM, MBBS, MD, PhD, FRANZCP, FAAHMS, Scientia Professor of Neuropsychiatry, UNSW Sydney & Co-director of the Centre for Healthy Brain Ageing (CHeBA), UNSW Sydney & Director of the Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, Australia & Co-Director of the Australian Dementia Network (ADNeT) & Director of the Centre for Research Excellence in Vascular Contributions to Dementia (CRE VCD)
RESEARCHER PROFILE
Filmed in Sydney, Australia | May 2026
Professor Perminder Sachdev graduated from the All-India Institute of Medical Sciences, New Delhi, in 1978 and completed his MD in Psychiatry there in 1983. Following time in New Zealand, he relocated to Australia, where he completed psychiatric training and a PhD at UNSW in 1991. His doctoral work examined ethnopsychological concepts in Māori culture. His early research focused on drug-induced movement disorders, including akathisia, tardive dyskinesia and neuroleptic malignant syndrome, while his later work has centred on dementia and pre-dementia syndromes, particularly neuroimaging, biomarkers and risk factors.
Professor Sachdev has held numerous leadership roles, including membership of the DSM-5 Neurocognitive Disorders Work Group, President of the International College of Geriatric Psychoneuropharmacology, and leadership positions within VASCOG, the International Neuropsychiatric Association, and the RANZCP Neuropsychiatry Section. He has also contributed extensively to Alzheimer’s Australia and Tourette syndrome advocacy.
His research interests span neuropsychiatric disorders of ageing, vascular and Alzheimer’s dementia, mild cognitive impairment, brain stimulation therapies, neuroimaging, Tourette syndrome and adult ADHD. In 2012, he co-founded CHeBA and leads major longitudinal studies, including the Sydney Memory and Ageing Study, alongside international consortia such as COSMIC, STROKOG and ICC-Dementia.
His achievements have been widely recognised, including appointment as a Member of the Order of Australia (2011), Fellow of the Australian Academy of Health and Medical Sciences (2015), and recipient of the Ryman Prize (2022) for contributions to ageing research. He has also received the Lishman Oration Award (2024) and a Lifetime Achievement Award (2025).
Professor Sachdev has authored over 1,000 journal articles, multiple books, and a book of poetry.
Source: Supplied
https://orcid.org/0000-0002-3421-4176
-
Tyrosine Kinases in cancer recurrence
Dr Yu Yu leads the Oncology and Gynaecology Research Program at Curtin Medical Research Institute . Dr Yu is also a senior research fellow at Curtin Medical School.
Dr Yu Yu’s laboratory is working on better ways to treat cancers, particularly ovarian cancers which are resistant to conventional chemotherapy. The aims are for better informed treatment choice and reducing unnecessary exposure to ineffective chemotherapy and its potential adverse effects.
-
ROCK-induced early-onset bowel cancer progression
Professor Michael Samuel is a cell biologist whose research interest is in understanding how cancer mechanobiology influences the tumour microenvironment, thereby promoting tumour progression. He is Professor of Matrix Biology at the University of South Australia, Adelaide and heads the Tumour Microenvironment Laboratory at the Centre for Cancer Biology and the Cancer Mechanotherapies Laboratory at the Basil Hetzel Institute for Translational Health Research.
-
Food and fasting periods as medicine to prevent disease
Professor Leonie Heilbronn is based at the South Australian Health and Medical Research Institute (SAHMRI), where she leads the Obesity and Metabolism laboratory. Her research is at the interface between basic and clinical science. She is internationally recognised for her work in nutritional modulation in humans and has made major contributions to our current understanding of mechanisms underlying conditions such as insulin resistance, particularly inflammation and lipid metabolism. She has also contributed significantly to current concepts of caloric restriction (CR), intermittent fasting (IF) and time restricted eating (TRE) in humans. She has published more than 110 peer reviewed papers in scientific journals and is an Associate Editor of Obesity, and Obesity Research and Clinical Practice.
