BRAIN AGEING, DEMENTIA AND PSYCHIATRIC DISORDERS
Professor Perminder S. Sachdev AM, MBBS, MD, PhD, FRANZCP, FAAHMS, Scientia Professor of Neuropsychiatry, UNSW Sydney & Co-director of the Centre for Healthy Brain Ageing (CHeBA), UNSW Sydney & Director of the Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, Australia & Co-Director of the Australian Dementia Network (ADNeT) & Director of the Centre for Research Excellence in Vascular Contributions to Dementia (CRE VCD)
RESEARCHER PROFILE
Filmed in Sydney, Australia | May 2026
Professor Perminder Sachdev graduated from the All-India Institute of Medical Sciences, New Delhi, in 1978 and completed his MD in Psychiatry there in 1983. Following time in New Zealand, he relocated to Australia, where he completed psychiatric training and a PhD at UNSW in 1991. His doctoral work examined ethnopsychological concepts in Māori culture. His early research focused on drug-induced movement disorders, including akathisia, tardive dyskinesia and neuroleptic malignant syndrome, while his later work has centred on dementia and pre-dementia syndromes, particularly neuroimaging, biomarkers and risk factors.
Professor Sachdev has held numerous leadership roles, including membership of the DSM-5 Neurocognitive Disorders Work Group, President of the International College of Geriatric Psychoneuropharmacology, and leadership positions within VASCOG, the International Neuropsychiatric Association, and the RANZCP Neuropsychiatry Section. He has also contributed extensively to Alzheimer’s Australia and Tourette syndrome advocacy.
His research interests span neuropsychiatric disorders of ageing, vascular and Alzheimer’s dementia, mild cognitive impairment, brain stimulation therapies, neuroimaging, Tourette syndrome and adult ADHD. In 2012, he co-founded CHeBA and leads major longitudinal studies, including the Sydney Memory and Ageing Study, alongside international consortia such as COSMIC, STROKOG and ICC-Dementia.
His achievements have been widely recognised, including appointment as a Member of the Order of Australia (2011), Fellow of the Australian Academy of Health and Medical Sciences (2015), and recipient of the Ryman Prize (2022) for contributions to ageing research. He has also received the Lishman Oration Award (2024) and a Lifetime Achievement Award (2025).
Professor Sachdev has authored over 1,000 journal articles, multiple books, and a book of poetry.
Source: Supplied
https://orcid.org/0000-0002-3421-4176
-
Metabolic phenotyping, lipidomics & bioinformatics in dementia
Dr Luke Whiley is a dementia researcher whose work focuses on understanding how the body’s metabolism, particularly the biology of fats known as lipids, influences our health throughout ageing.
His research explores how the body responds to illness, lifestyle, and environmental stress at a chemical level, and how these responses shape longterm disease risk. Using advanced blood-based measurement technologies, Dr Whiley studies thousands of small molecules at once to build a snapshot of a person’s metabolic health. By combining these measurements with data science approaches, his work identifies biological pathways that become disrupted in disease, providing insight into why some people are more vulnerable to conditions such as dementia.
-
Nutraceutical and pharmacological intervention in neurological disorders
Dr Virginie Lam is a neuroscientist and cerebrovascular biologist with over 15 years of research experience, including more than seven years post-PhD. She co-leads the Neurovascular and Metabolic Diseases Laboratory at the Curtin Medical Research Institute and holds an affiliate appointment at the Perron Institute for Neurological and Translational Science. Her research focuses on the interface between neurovascular health, cognitive function, and therapeutic translation in neurodegenerative disorders.
-
Cancer survivorship and exercise oncology
Professor Sandra Hayes is the Director of Research at Cancer Council Queensland (CCQ), where she leads a comprehensive cancer research program encompassing cancer epidemiology, prevention, detection, treatment, and survivorship.
With a BAppSci (Hons) and a PhD in exercise oncology, Professor Hayes’s expertise lies in quantifying the impact of cancer diagnosis and treatment on physical and psychosocial wellbeing, quality of life, and survival. She also evaluates innovative supportive care strategies, particularly exercise, to improve post-cancer lives.
