IMMUNE MECHANISMS OF COELIAC DISEASE AND GLUTEN-RELATED DISORDERS
With
Professor Jason Tye-Din,
Director, Snow Centre for Immune Health &
Head of the Coeliac Research Laboratory at WEHI &
Gastroenterologist, Royal Melbourne Hospital &
Clinician Researcher,
Melbourne, Australia
RESEARCHER PROFILE
Filmed in Melbourne | September 2026
Professor Jason Tye-Din is head of the Coeliac Research Laboratory at WEHI and a gastroenterologist at the Royal Melbourne Hospital. His expertise spans the immune mechanisms of coeliac disease, clinical care of gluten-related disorders, diagnostic discovery and pre-clinical and clinical drug development. His work aims to improve the health and quality of life of people suffering gastrointestinal immune diseases, particularly those caused by gluten and other foods.
Professor Tye-Din is a Principal Research Fellow at the University of Melbourne, Honorary Research Fellow at the Murdoch Children’s Research Institute and is involved in multiple leadership and advisory roles, including to the World Health Organisation and industry.
As a recognised leader in immunology and translational science, Professor Tye-Din’s research has been widely published. Most recently, he led the development of a ground-breaking blood test that has the potential to transform the way coeliac disease is diagnosed.
Source: Supplied
https://orcid.org/0000-0001-7687-9654-
Nanoparticles & microparticles to combat antimicrobial resistance
Dr Anjana Jayasree is an emerging research leader in biomaterials, tissue engineering and nanotechnology, recognised internationally for her innovative work on antimicrobial nanoparticles and regenerative therapies. A Postdoctoral Research Fellow at The University of Queensland, she operates at the intersection of materials science, drug delivery and cellular biology, developing advanced metallic-based nanotechnologies to improve both human and animal health outcomes. Her expertise spans nanoparticle synthesis, cell–material interactions, and the design of sophisticated in vitro models to investigate soft-tissue integration, osseointegration, angiogenesis and biofilm formation.
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Stem cell therapies for enteric neuropathies
Dr Stamp is a Group Leader in the Department of Anatomy and Physiology at the University of Melbourne, Australia. Dr Stamp’s PhD research (with Prof Martin Pera, Monash University) focused on the derivation of hepatopancreatic progenitors from human embryonic stem cells. He then joined the lab of Dr Don Newgreen at the Murdoch Childrens Research Institute where he began working on development of the enteric nervous system (ENS), before joining Prof Heather Young’s lab at the University of Melbourne, where he focused on developing a stem cell therapy to treat gut motility disorders such as the paediatric enteric neuropathy Hirschprung disease.
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Engineering bacteria to detect colorectal cancer cells
An international team of researchers from Adelaide and the United States has engineered bacteria capable of detecting mutated DNA released from colorectal cancer cells, opening the door to faster disease detection.
