IMMUNE MECHANISMS OF COELIAC DISEASE AND GLUTEN-RELATED DISORDERS
With
Professor Jason Tye-Din,
Director, Snow Centre for Immune Health &
Head of the Coeliac Research Laboratory at WEHI &
Gastroenterologist, Royal Melbourne Hospital &
Clinician Researcher,
Melbourne, Australia
RESEARCHER PROFILE
Filmed in Melbourne | September 2026
Professor Jason Tye-Din is head of the Coeliac Research Laboratory at WEHI and a gastroenterologist at the Royal Melbourne Hospital. His expertise spans the immune mechanisms of coeliac disease, clinical care of gluten-related disorders, diagnostic discovery and pre-clinical and clinical drug development. His work aims to improve the health and quality of life of people suffering gastrointestinal immune diseases, particularly those caused by gluten and other foods.
Professor Tye-Din is a Principal Research Fellow at the University of Melbourne, Honorary Research Fellow at the Murdoch Children’s Research Institute and is involved in multiple leadership and advisory roles, including to the World Health Organisation and industry.
As a recognised leader in immunology and translational science, Professor Tye-Din’s research has been widely published. Most recently, he led the development of a ground-breaking blood test that has the potential to transform the way coeliac disease is diagnosed.
Source: Supplied
https://orcid.org/0000-0001-7687-9654-
Exercise therapy for metabolic dysfunction-associated steatotic liver disease
Dr Shelley Keating is a Senior Lecturer in Clinical Exercise Physiology and Accredited Exercise Physiologist from the School of Human Movement and Nutrition Sciences at the University of Queensland. With a strong grounding in exercise metabolism and body composition, Dr Keating’s research centres on the utility of exercise as a therapy for obesity and related cardiometabolic conditions, notably metabolic dysfunction-associated steatotic liver disease (MASLD).
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Paediatric haemorrhage and airway procedures
Dr Shane George is a paediatric critical care physician working in paediatric emergency medicine and paediatric intensive care at Gold Coast University Hospital. He is the clinical lead for children’s critical care research for Gold Coast Health, and is a Senior Lecturer at The University of Queensland and Griffith University.
Associate Professor George is also an active clinician researcher on topics that span both emergency medicine and PICU practice including safety in emergency intubation, sepsis, haemostatic resuscitation in children and respiratory support therapies.
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Identification & characterisation of molecular drivers of therapeutic resistance
Professor Pieter Eichhorn is an internationally experienced cancer biologist and research leader whose career has been defined by high-impact contributions at the interface of functional genomics, translational oncology, and research infrastructure strategy.
He completed his PhD at the University of Newcastle upon Tyne, contributing to the cloning of the gene associated with Cornelia de Lange Syndrome, before undertaking postdoctoral training at the Netherlands Cancer Institute in the laboratory of René Bernards. There, he performed pioneering functional genetic screens that identified key regulators of oncogenesis and therapy resistance, including critical roles for the PI3K signalling pathway in resistance to targeted breast cancer therapies.
