RESEARCHER PROFILE
Professor Sant-Rayn Pasricha (Filmed April 2024)
Study lead and Acting WEHI Deputy Director
WEHI (Walter and Eliza Hall Institute of Medical Research)
Clinical Haematologist Royal Melbourne Hospital & Peter MacCallum Cancer Centre
Professor Sant-Rayn Pasricha is the Acting Deputy Director at the Walter Eliza Hall Institute of Medical Research in Melbourne, Australia. He is also a clinical haematologist at the Royal Melbourne Hospital and the Peter MacCallum Cancer Centre. From a young age, Prof Pasricha dreamed of becoming a doctor and found joy in learning about the human body and how to care for patients. After completing medical school, he developed a passion for working in low and middle-income countries, which led him to spend time working in East Timor, India, and Central Australia with First Nations communities.
Prof Pasricha went on to specialise in haematology, which covers a wide range of fields, including cancer biology, immunology, transplant, nutrition, pathology, and red cell blood transfusion. He completed his haematology training and earned a PhD in global health, which allowed him to explore his interests in public health, global health, and haematology. Prof Pasricha focused his research on the significant and common issue of anaemia, particularly in low-income countries. He conducted field studies in the villages of Karnataka, India, and spent five years working in the lab at the University of Oxford to understand iron biology.
Currently, Pasricha runs his own lab at WEHI, where he serves as a lab and division head, conducting anaemia research. His lab covers a range of basic science research areas, including exploratory biology on how red blood cells are made, iron biology, and the role of inflammation in anaemia. Additionally, his lab conducts global trials in Africa and South Asia to prevent and treat anaemia and nutritional disorders in children and pregnant women.
Prof Pasricha’s lab completed a large analysis on haemoglobin thresholds to define anaemia, which informed the new World Health Organization guidelines on anaemia. The lab also conducts large randomised controlled field studies on ways to treat anaemia in pregnancy and young babies in Malawi and Bangladesh.
Prof Pasricha is passionate about improving the health of people in low-income countries and finding innovative solutions to improve the health of mothers and children in particular. He focuses on anaemia, nutrition, and exposure to infectious diseases. Prof Pasricha is also deeply curious about how the body works and how different systems interact with each other and the outside environment.
As a clinician scientist, Pasricha finds his job both busy and fulfilling. He enjoys taking care of patients, keeping up with breakthroughs in medicine, and running a research program. Prof Pasricha spends a substantial amount of time thinking about his work and planning the next experiment or study. Outside of work, he enjoys spending time with his three children and being involved in the community.
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Muscle Cell Communication and Repair
Dr. William Roman is a Group Leader at the Australian Regenerative Medicine Institute (ARMI) at Monash University. He obtained his PhD from Paris Descartes University and Freie University of Berlin, focusing on nuclear positioning during skeletal muscle development. Dr. Roman’s research journey has taken him across the globe, including postdoctoral work in Barcelona, tissue engineering in Lisbon, and a brief stint at Stanford University.
At ARMI, Dr. Roman leads innovative research on intercellular communication within muscle organs. His work involves growing human muscles on chips to understand how skeletal muscle cells interact with neurons and tendons. This research aims to develop better models for studying muscle diseases, drug screening, and even applications in cellular agriculture and biorobotics.
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ROCK-induced early-onset bowel cancer progression
Professor Michael Samuel is a cell biologist whose research interest is in understanding how cancer mechanobiology influences the tumour microenvironment, thereby promoting tumour progression. He is Professor of Matrix Biology at the University of South Australia, Adelaide and heads the Tumour Microenvironment Laboratory at the Centre for Cancer Biology and the Cancer Mechanotherapies Laboratory at the Basil Hetzel Institute for Translational Health Research.
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Therapy to prevent hepatocellular carcinoma in people with liver cirrhosis
Professor John Olynyk is a Gastroenterologist & Hepatologist with over 30 years’ experience, primarily at The Fiona Stanley & Fremantle Hospital Group. He planned the Gastroenterology and Hepatology Service for the Fiona Stanley Hospital and was Head Department from 2010 until 2020.
Professor John Olynyk was appointed as Associate Dean and Head of the Medical Discipline at Curtin University in 2023 until 2025 and is now Associate Director, Clinical Engagement, Curtin Medical Research Institute, Curtin University.
