IMMUNE MECHANISMS OF COELIAC DISEASE AND GLUTEN-RELATED DISORDERS
With
Professor Jason Tye-Din,
Director, Snow Centre for Immune Health &
Head of the Coeliac Research Laboratory at WEHI &
Gastroenterologist, Royal Melbourne Hospital &
Clinician Researcher,
Melbourne, Australia
RESEARCHER PROFILE
Filmed in Melbourne | September 2026
Professor Jason Tye-Din is head of the Coeliac Research Laboratory at WEHI and a gastroenterologist at the Royal Melbourne Hospital. His expertise spans the immune mechanisms of coeliac disease, clinical care of gluten-related disorders, diagnostic discovery and pre-clinical and clinical drug development. His work aims to improve the health and quality of life of people suffering gastrointestinal immune diseases, particularly those caused by gluten and other foods.
Professor Tye-Din is a Principal Research Fellow at the University of Melbourne, Honorary Research Fellow at the Murdoch Children’s Research Institute and is involved in multiple leadership and advisory roles, including to the World Health Organisation and industry.
As a recognised leader in immunology and translational science, Professor Tye-Din’s research has been widely published. Most recently, he led the development of a ground-breaking blood test that has the potential to transform the way coeliac disease is diagnosed.
Source: Supplied
https://orcid.org/0000-0001-7687-9654-
Unnecessary tests and treatments in low value critical care
Dr Gerben Keijzers is a Senior Staff Specialist Emergency Physician at the Gold Coast University Hospital Emergency Department. His research focus includes low-value care, which is in the area of unnecessary tests and treatments with minimal benefits. Dr Keijzers has contributed to over 100 publications and more than 20 grant applications. Through his involvement in multi-site collaborative research projects, he encourages critical thinking and curiosity among clinical staff, striving to enhance both patient care and the efficiency of healthcare resources.
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Identifying and treating autoimmune neurological disorders
Associate Professor Sudarshini Ramanathan is a neurologist and clinician scientist whose work focuses on autoimmune neurological disorders. Her research has helped identify new neurological syndromes due to antibody-mediated demyelination and encephalitis, and improve diagnostic tools and treatment guidelines for patients with autoimmune diseases affecting the brain, spinal cord, muscles and nerves.
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Hormone receptor positive breast cancer and therapy resistance
Prof Elgene Lim is a medical oncologist at St Vincent’s Hospital and Head of the Connie Johnson Breast Cancer Research Lab at the Garvan Institute. Following his PhD at the Walter & Eliza Hall Institute where he identified the aberrant cells in carriers of the BRCA1 mutant gene, a hereditary breast cancer syndrome as the culprit cells giving rise to breast cancer, he furthered his research and clinical training at the Dana-Farber Cancer Institute and Harvard Medical School. He was awarded the National Breast Cancer Foundation Practitioner Fellowship in 2014 and returned from Boston to Australia. In 2017, he was awarded the inaugural National Breast Cancer Foundation Endowed Chair, and subsequently appointed the Principal Cancer Theme Lead at UNSW.
