IDENTIFYING AND TREATING AUTOIMMUNE NEUROLOGICAL DISORDERS
With
Associate Professor Sudarshini (Darshi) Ramanathan,
Neurologist & Head of Translational Neuroimmunology Group
Faculty of Medicine and Health
University of Sydney, Australia
RESEARCHER PROFILE
Filmed in Sydney, Australia | April 2026
Associate Professor Sudarshini Ramanathan is a neurologist and clinician scientist whose work focuses on autoimmune neurological disorders. Her research has helped identify new neurological syndromes due to antibody-mediated demyelination and encephalitis, and improve diagnostic tools and treatment guidelines for patients with autoimmune diseases affecting the brain, spinal cord, muscles and nerves.
Associate Professor Ramanathan’s research program aims to improve our understanding of underlying disease pathogenesis with a focus towards ‘precision medicine’ in neuroimmunology – both with diagnosis and therapeutics. Her research focuses on defining the clinical, radiological, and immunophenotypic profiles of specific pathogenic autoantibodies; understanding what triggers autoimmunity and disruption of immune tolerance; and the cellular and humoural mechanisms of action of autoantibodies and how this might be translated into refining novel therapeutic approaches.
Her work thus far has resulted in the enhanced recognition of novel treatable neurological conditions, important biological insights into the pathophysiology of these disorders, and the development of diagnostic criteria and therapeutic approaches to improve outcomes in vulnerable patients who otherwise risk chronic disability.
Associate Professor Ramanathan heads the Translational Neuroimmunology Group at the Faculty of Medicine and Health, University of Sydney; and also runs a neuroimmunology clinic at Concord Hospital. She supervises and mentors a research team of PhD and Masters candidates, postdoctoral fellows, and clinician researchers. Her research has been recognised by the Leonard Cox Award for Excellence in Neuroscience research and the NSW Premier’s Prize Award for Early Career Researchers (Biological Sciences) in 2022.
Source: Supplied
https://orcid.org/0000-0002-0294-9768
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Funding the best brains to beat brain cancer
The Charlie Teo Foundation is dedicated to funding and advancing research into brain cancer, with a particular focus on developing more effective treatments and finding a cure for this devastating disease.
Since its inception, the foundation has committed nearly $15 million to brain cancer research, funding notable projects in Australia and the United States. These projects explore innovative approaches to understand and treat brain cancer more effectively, with a focus on translating findings from animal studies to human applications. Charlie’s dedication to finding solutions for this devastating disease remains unwavering as he travels frequently to collaborate with global researchers. -
Corneal and Ocular Surface Immunology and Regeneration
Assoc Professor Holly Chinnery’s career in ocular immunology began with a focus on animal models; however, it has recently transitioned into clinical imaging studies involving human research participants. The ability to visualise the immune system and sensory nerves in the human cornea represents a significant advantage in corneal immunology and neuroimmunology research.
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Relationship between language-literacy skills and mental health
In an innovative move towards enhancing mental health services, Associate Professor Amanda Neil and team, supported by the RHH Research Foundation, are undertaking a crucial study on language-literacy skills of patients within mental health care settings. This year-long project, which commenced in April 2024, seeks to unravel to what extent, where and for whom language-literacy skills are being considered in Tasmanian mental health service provision.
