NEONATAL RESPIRATORY TRIALS IN SICK & PRETERM NEWBORN INFANTS
Professor Brett J. Manley, Consultant Neonatologist
Mercy Hospital For Women, Melbourne & Professor of Neonatal Medicine, Department of Obstetrics, Gynaecology and Newborn Health, University of Melbourne, Australia
RESEARCHER PROFILE
Filmed in Melbourne, Australia | August 2025
Professor Brett J. Manley is a Consultant Neonatologist at the Mercy Hospital for Women in Melbourne, Australia, and a Professor of Neonatology in the Department of Obstetrics, Gynaecology and Newborn Health at The University of Melbourne. His research is supported by a fellowship from the National Health and Medical Research Council (NHMRC), Australia.
He divides his work time between being a clinician in the neonatal intensive care unit (NICU), and a clinical researcher. He is passionate about caring for sick and preterm newborn infants and contributing to the evidence base for their care, to improve their shorter- and longer-term outcomes.
Prof Manley leads and collaborates on large national and international randomised clinical trials in neonatology. He previously collaborated on 4 randomised trials of nasal high-flow as non-invasive respiratory support for preterm and term infants, all of which were published in N Engl J Med. Recently he led the PLUSS trial of intratracheal budesonide for extremely preterm infants, that recruited in 21 NICUs across 4 countries, the results of which were published in JAMA. PLUSS was awarded the Australian Clinical Trials Alliance Trial of the Year in 2025. Another passion of his is mentoring and supervising early career researchers to undertake their own clinical trials.
Source: Supplied
https://orcid.org/0000-0003-0212-7956
-
Personalised approaches to lung therapy
Dr. Adams’ research focus is on lung cancer, which is the deadliest of all cancers worldwide. He is working towards developing personalised approaches to pinpoint a therapy that is going to be most effective for the person with that disease. Dr. Adams’ research is focusing on chemotherapy and targeted therapy, and he is trying to identify upfront which of those tumours are likely to be resistant to the therapy. He then identifies strategies that will resensitize or increase the sensitivity of the tumour to the standard of care that is targeted therapy or chemotherapy.
-
Lymphoma, Myeloma and Genomics
Professor Dipti Talaulikar is a clinical and laboratory haematologist with expertise in genomics, working at Canberra Health Services, and Professor at ANU. She has a clinical and research interest in lymphoma, myeloma and genomics, and has authored close to 100 peer reviewed papers, including several clinical guidelines that have had a significant impact on clinical practice.
-
Anne O’Neill
STATE GOVERNMENT SUPPORTING MEDICAL RESEARCH
@ NSW HEALTH, NEW SOUTH WALES AUSTRALIA
