NEW TREATMENT OPTIONS UNDER INVESTIGATION FOR PELVIC ORGAN PROLAPSE Design of next generation meshes using degradable polymers and stem cell based surgical constructs
Pelvic organ prolapse (POP) develops when tissues, pelvic floor muscles and ligaments that support the pelvic organs (bladder, uterus and bowel) are damaged, usually in childbirth. This injury causes the organs to shift, or ‘drop’, into the vagina or event outside of the body. This can lead to debilitating symptoms including poor bladder or bowel control and pain during sex
POP Facts
- 1 in 4 women globally in their 40s live with POP
- 1 in 2 women over 50 years of age live with POP
- $200 million annual cost to the Australian healthcare system
POP is a lifelong, potentially debilitating condition. Despite the high prevalence, there is no cure for POP.
Dr Shayanti Mukherjee, Research Group Head, Translational Tissue Engineering at the with her team at Hudson Institute of Medical Research is developing new ways to prevent and potential cure pelvic organ prolapse (POP). The technology aims to ultimately lead to safer and more effective treatment for women with pelvic organ prolapse (POP) using a woman’s own stem cells to boost the effectiveness of a degradable mesh.
Dr Shayanti Mukherjee specialises in innovative cell-based therapies for pelvic floor disorders and birth trauma injuries.
Dr Mukherjee’s research uses a woman’s own stem cells to create a 3D-printed degradable mesh, promising to avoid the complications that have plagued previous synthetic non-degradable meshes.
“By integrating cutting-edge techniques like electrospinning and 3D printing of materials and cells, I aim to revolutionise maternal urogynaecological health, offering transformative solutions and improving the wellbeing of women affected by this prevalent issue.”
“This research has the potential to revolutionise therapies for pelvic floor regeneration and enable personalised medicine for women,” she said.
“By advancing innovative cell-based therapies, we are on the brink of transforming the landscape of maternal urogynaecological health, promising a brighter and healthier future for women across the globe,” said Dr Mukherjee.
Source: Hudson Institute of Medical Research
-
Addressing Wound Management
The cost of chronic wounds in Australia is estimated to be $3 Billion per year, impacting 420,000 Australians. Not only is this a national economic concern, but more importantly, is the suffering the person may be going through.
Australian Health Journal met with Hayley Ryan, Board Director and Chair at Wounds Australia and Director at WoundRescue to hear her work in chronic wound management, palliative wounds and pressure injury prevention to comfort those living with a wound.
-
Integrating oral health care across non-dental professionals
Poor oral health can contribute to or exacerbate several systemic health conditions due to the close connection between oral bacteria, inflammation, and systemic processes. These conditions include cardiovascular health, diabetes, respiratory health, cognitive health, pregnancy and birth outcomes.
-
Challenge advances health technologies and medical devices in the MedTech sector
In July IDE Group launched the 2027 Building Better Futures for Health (BBFH) Challenge, a program supporting early-stage MedTech innovators move from concept to commercialisation. Delivered with Medical Technology Association of Australia’s (MTAA) MedTech Compass, the 2027 program marks 10 years of impact.
Now in its 11th year, BBFH supports researchers, clinicians, entrepreneurs and early-stage ventures tackling urgent healthcare needs. Selected teams will pitch to industry experts, gaining feedback to strengthen commercial potential.
