RESEARCHER PROFILE
Georgina Hughes,
Pharmacist & PhD Candidate
University of South Australia Clinical and Health Sciences
Registry of Senior Australians (ROSA)
South Australian Health and Medical Research Institute
Georgina Hughes is a pharmacist & PhD Candidate with the University of South Australia Clinical and Health Sciences and the Registry of Senior Australians (ROSA), undertaking research at South Australian Health and Medical Research Institute (SAHMRI).
Georgina’s PhD study and first published paper was on how to improve the safe and effective use of antidepressant medicines and optimise quality use of medicines in older people accessing residential aged care.
The study, published in the Journal of American Medical Directors Association (JAMDA), was led by Georgina, in collaboration with Professor Maria Inacio and Associate Professor Janet Sluggett. It’s Australia’s first national study investigating the use of antidepressants among older people living in residential aged care homes across the country, analysing the de-identified data of 779,659 residents from 3,371 aged care homes, between 2006 and 2019.
“We found antidepressants were used by 46.1% of residents in 2006 and this increased to 58.5% of residents in 2019,” Ms Hughes said.
“Nearly six in every ten residents of aged care homes are using an antidepressant, which is much higher than use in the general older population.”
The use of antidepressant medicines among older people in aged care homes in Australia is high, and there is a need for better mental health support and safer use of antidepressants to improve clinical care and health outcomes for older people.
Antidepressant medicines can have side effects, especially in older people, and Australia is one of the largest consumers globally.
Almost 60% of aged care home residents are using antidepressant medicines, prompting the need to investigate the reasons for such high usage.
Georgina talks to how big data is crucial in understanding and improving the use of antidepressant medicines in aged care, leading to better clinical care and health outcomes for older people in Australia.
Georgina is passionate about practice-informing, translational and innovative research to improve quality use of medicines and health outcomes.
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Genetic alterations in prostate cancer initiation and progression
Watch Dr Kelsie Raspin, a dedicated Postdoctoral Research Fellow specialising in Cancer Genetics at Menzies Institute for Medical Research, University of Tasmania, talk on bridging a critical knowledge gap in the understanding of genetic alterations implicated in prostate cancer initiation and its progression into metastatic forms.
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Outcomes of Corneal Allergenic Intrastromal Ring Segment (CAIRS) Surgery
Dr David Gunn is an ophthalmologist specialising in cornea, cataract, and refractive surgery at the Queensland Eye Institute and Focus Vision in Brisbane, Queensland. His journey into ophthalmology began during medical school, inspired by a mentor. His current research examines outcomes for patients undergoing Corneal Allergenic Intrastromal Ring Segment (CAIRS) surgery.
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De-prescribing medications in older adults with dementia
Dr. Daniel Hoyle is a Senior Lecturer in Therapeutics and Pharmacy Practice at the School of Pharmacy and Pharmacology, University of Tasmania. He is also an experienced clinical pharmacist with expertise in medication management in older people. Dr. Hoyle’s research interests focus on improving medicine use in older people with dementia.
