MUSCLE CELL COMMUNICATION AND REPAIR
With
Dr. William Roman
Group Leader,
Australian Regenerative Medicine Institute (ARMI)
Monash University, Melbourne, Australia
RESEARCHER PROFILE
Filmed in Melbourne | April 2025
Dr. William Roman is a Group Leader at the Australian Regenerative Medicine Institute (ARMI) at Monash University. He obtained his PhD from Paris Descartes University and Freie University of Berlin, focusing on nuclear positioning during skeletal muscle development. Dr. Roman’s research journey has taken him across the globe, including postdoctoral work in Barcelona, tissue engineering in Lisbon, and a brief stint at Stanford University.
At ARMI, Dr. Roman leads innovative research on intercellular communication within muscle organs. His work involves growing human muscles on chips to understand how skeletal muscle cells interact with neurons and tendons. This research aims to develop better models for studying muscle diseases, drug screening, and even applications in cellular agriculture and biorobotics.
Dr. Roman’s recent breakthrough in muscle repair mechanisms, independent of stem cells, has potential implications for preserving muscle function in exercise, diseases, and aging. His lab employs cutting-edge techniques such as cell biology, tissue engineering, and spatial transcriptomics.
In recognition of his groundbreaking work, Dr. Roman was awarded the prestigious 2024 Metcalf Prize for Stem Cell Research, highlighting his significant contributions to the field of regenerative medicine.
Dr Roman’s research has been funded by the Baker Foundation, Australia’s NHMRC and more recently the National Stem Cell Foundation.
Source: Supplied and supplemented
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Mental health research on first responders in regional, rural and remote Australia
Dr Rikki Jones has been awarded to date a total of over $430,000 in research funding. She is currently leading four large national research teams focusing on rural health and sustainable rural health workforce (include mental health of first responders, sexual violence in rural Australia, virtual simulated nursing placements, and nursing students experience with online learning, connection and transitioning to practice).
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Clinical pathways for acute care in Tasmanian Emergency Departments
Assoc Prof Viet Tran has built Emergency Medicine Research in Tasmania from the ground up, which has culminated in the success of a AUD$3 million Australian Government Medical Research Futures Fund grant looking into the Implementation of Clinical Pathways for Acute Care in Tasmania project. Dr Tran is also the Emergency Medicine Discipline lead within the Tasmanian School of Medicine and has key roles to play within Emergency Medicine training. He feels privileged to be able to teach and mentor across the whole spectrum of becoming a doctor, from watching students grow into junior doctors, senior registrar and as fellow medical specialists.
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Next-generation NK cell-based immunotherapies for hard-to-treat cancers
Associate Professor Fernando Guimaraes is an internationally recognised leader in cancer immunotherapy and natural killer (NK) cell biology. Based at The University of Queensland, he leads innovative research focused on developing next-generation NK cell-based immunotherapies for hard-to-treat cancers, including sarcomas and neuroblastoma.
