RELATIONSHIP BETWEEN MENTAL ILLNESS AND MENTAL WELLBEING
Dr Matthew Iasiello, Head of Data and Research Translation, Be Well Co,
SAHMRI (South Australian Health and Medical Research Institute) &
Post Doctoral Researcher, University of Adelaide
RESEARCHER PROFILE
Filmed in Adelaide, South Australian | December 2024
Since 2015, Dr Matthew Iasiello has been working on the development and dissemination of mental wellbeing interventions across the Australian community at the South Australian Health and Medical Research Institute (SAHMRI). His PhD research was designed specifically to strengthen the translational work conducted by SAHMRI, and to solve problems that represented gaps in the literature that were arising when delivering mental wellbeing interventions into the community. The impact and relevance of Dr Iasiello’s work has been demonstrated with invited presentations at international academic conferences, and multiple media stories with significant online engagements.
Dr Iasiello’s research investigates the dual-continua model, an innovative model of mental health. The dual-continua model of mental health suggests that mental illness and mental wellbeing reflect distinct continua, rather than the extreme ends of a single spectrum. This novel conceptualisation of the relationship between mental illness and mental wellbeing has significant implications in the way we promote mental health, and prevent, treat, and recover from mental illness. However, little is known about the evidence validating the model, and whether this evidence supports the implications that have been proposed in the literature.
Dr Iasiello’s PhD project synthesises the relevant evidence supporting the model, provides further evidence of the role of mental wellbeing in the recovery of mental illness, and addresses important limitations in the current assessment of mental wellbeing in the context of psychological distress and mental illness.
He is engaged in the development of mental wellbeing services and products that emerge directly from the new knowledge generated from his PhD, translated into the community via SAHMRI. This has resulted in the development and evaluation of the Be Well Plan (https://www.bewellco.io/bwt), and evidence-based wellbeing intervention (over 5,000 participants since 2020), and the Be Well Tracker https://www.bewellco.io/be-well-plan, a free online assessment platform that Australians can use to assess and monitor their mental health (20,000 users since 2019).
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Stem cells used for age-related macular degeneration
Dr. Jenna Hall is a passionate and accomplished biologist with expertise in induced pluripotent stem cell (iPSC) culture, disease modelling, and high-throughput automated systems. She recently earned her PhD from the University of Melbourne, where her research focused on using iPSC-derived retinal pigment epithelium (RPE) cells to study age-related macular degeneration. Dr Hall’s technical skillset spans manual and automated cell reprogramming and differentiation, quantitative microscopy-based phenotyping, and large scale -omics analysis.
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Links investigated between poor sleep and onset of dementia
Watch Samantha Bramich, a PHD candidate at the Wicking Dementia Research and Education Centre, University of Tasmania talk on identify the prevalence of rapid eye movement sleep behaviour disorder (RBD) in Tasmania and how poor sleep contributes to the onset of dementia and other diseases.
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Investigating invasive lobular carcinoma and metaplastic breast cancer sub-types
Assoc Prof McCart Reed is the scientific lead on an MRFF-funded (Medical Research Future Fund) genomics program investigating the potential for the application of Whole Genome Sequencing in the breast cancer care pathway in Australia, ‘Q-IMPROvE’. She applies genomics and spatial transcriptomics methodologies to archival clinical samples to understand the differences between tumour types and their potential for treatment. Amy is passionate about clinical research, biobanking and precision oncology. In addition to her breast cancer research portfolio, she is on the steering committee for the Brisbane Breast Bank and the Scientific Advisory Board for Breast Cancer Trials.
