INFLUENCE OF GUT MICROBES AND INFLAMMATION ON BRAIN FUNCTION AND BEHAVIOUR IN AUTISM
With
Angela Renata Jiménez Perez,
PhD Candidate,
Gut-Brain Axis Laboratory, RMIT University
Melbourne, Australia
RESEARCHER PROFILE
Filmed in Melbourne, Australia | August 2026
Third-year PhD candidate Angela Jimenez is part of the Gut-Brain Axis Laboratory at RMIT University in Melbourne, Australia. Angela holds a bachelor’s degree in neuroscience (Honours) from the National Autonomous University of Mexico (UNAM), and her doctoral research is currently supported by the RMIT–Mexico International Scholarship program.
Angela’s project focuses on describing how gut microbes and inflammation influence brain function and behaviour in autism. Using a mouse model that carries an autism-associated gene variant, she investigates how inflammatory challenges alter behaviour and brain function. Her work has been presented at both national and international forums, including the Australasian Neuroscience Society (ANS) annual meeting in 2025 and the FENS Forum 2026 in Barcelona.
A central aspect of her work explores how metabolites produced by bacteria in the gut can influence neurobiological responses, with the long-term aim of identifying microbiota-targeted therapeutic strategies for individuals with high-support needs autism.
Angela’s broader scientific objective is to advance mechanistic understanding of how other systems, particularly the immune system and microbiome, contribute to behavioural outcomes in neurodevelopmental conditions. She aims to bridge fundamental neurobiology with translational approaches that can lead to future therapeutic development.
Source: Supplied
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Touched by bowel cancer and chasing science outcomes
Dr Josephine Wright is a Senior Research Fellow in the Gut Cancer group. She has been developing a translational network of labs, hospitals and clinics to enable validation of new approaches to prevent and treat colorectal and gastric cancer. Her key focus is studying human tumour organoids to better personalise therapy in cancer.
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Dietary Interventions Influencing Neurological Outcomes
With over a decade of experience as a dietitian and nutritionist, Carolina Blagojevic Castro specialises in providing personalised dietary guidance and customised meal planning tailored to meet each client’s unique health needs. She is known for her engaging and educational presentations on topics related to health and nutrition, sharing practical, evidence-based insights with both community groups and professional audiences.
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Enhancing occupational therapy service provision with military veterans
Prof McKinstry was instrumental in the development of the occupational therapy course at the La Trobe University’s Bendigo campus and also the establishment of the Rural Health School.
Prof McKinstry’s research focus is on health workforce, particularly developing a sustainable rural health workforce through recruitment of rural students for health courses, innovative and flexible delivery of health courses, telehealth and emerging areas of practice for occupational therapists.
