INFLUENCE OF GUT MICROBES AND INFLAMMATION ON BRAIN FUNCTION AND BEHAVIOUR IN AUTISM
With
Angela Renata Jiménez Perez,
PhD Candidate,
Gut-Brain Axis Laboratory, RMIT University
Melbourne, Australia
RESEARCHER PROFILE
Filmed in Melbourne, Australia | August 2026
Third-year PhD candidate Angela Jimenez is part of the Gut-Brain Axis Laboratory at RMIT University in Melbourne, Australia. Angela holds a bachelor’s degree in neuroscience (Honours) from the National Autonomous University of Mexico (UNAM), and her doctoral research is currently supported by the RMIT–Mexico International Scholarship program.
Angela’s project focuses on describing how gut microbes and inflammation influence brain function and behaviour in autism. Using a mouse model that carries an autism-associated gene variant, she investigates how inflammatory challenges alter behaviour and brain function. Her work has been presented at both national and international forums, including the Australasian Neuroscience Society (ANS) annual meeting in 2025 and the FENS Forum 2026 in Barcelona.
A central aspect of her work explores how metabolites produced by bacteria in the gut can influence neurobiological responses, with the long-term aim of identifying microbiota-targeted therapeutic strategies for individuals with high-support needs autism.
Angela’s broader scientific objective is to advance mechanistic understanding of how other systems, particularly the immune system and microbiome, contribute to behavioural outcomes in neurodevelopmental conditions. She aims to bridge fundamental neurobiology with translational approaches that can lead to future therapeutic development.
Source: Supplied
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Stem cells used for age-related macular degeneration
Dr. Jenna Hall is a passionate and accomplished biologist with expertise in induced pluripotent stem cell (iPSC) culture, disease modelling, and high-throughput automated systems. She recently earned her PhD from the University of Melbourne, where her research focused on using iPSC-derived retinal pigment epithelium (RPE) cells to study age-related macular degeneration. Dr Hall’s technical skillset spans manual and automated cell reprogramming and differentiation, quantitative microscopy-based phenotyping, and large scale -omics analysis.
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Novel forms of brain stimulation & psychedelic assisted psychotherapy
Professor Paul Fitzgerald is the Head of the School of Medicine and Psychology at the Australian National University. He is an academic psychiatrist with a MBBS degree, Masters of Psychological Medicine and research PhD. He has conducted an extensive range of experimental studies and clinical trials, focused on the development of novel treatment options for patients with mental health conditions such as depression, schizophrenia, obsessive compulsive disorder, PTSD, autism and Alzheimer’s disease.
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Dr Paul Griffin
MATER HEALTH SERVICES, QUEENSLAND, AUSTRALIA
