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Landmark research projects tackle critical issues in emergency healthcare

For two decades, the demand for emergency department services in Australia has outpaced population growth and wait times have increased. In 2022-2023 more than 8.8 million emergency department presentations occurred nationwide.

While demand is a contributing factor, EDs are currently being impacted by various factors across the entire health system.

The Emergency Medicine Foundation (EMF) is a non-profit organisation funding innovative Australian research that improves the way people are cared for in a medical emergency. The aim of the research is to deliver better and more effective health services to save lives and money.

Empowering underprivileged communities with sustainable health

Dr Gaj Panagoda, CEO of Xstitch Health, has a diverse medical background and is working to improve health systems for underprivileged communities. In the Australian Health Journal’s People In Health Care series, he talks about the changes needed in community-based care using a project based approach,

According to Dr Panagoda, there is a need for a shift towards community-based care and collaboration with stakeholders in the healthcare system, and the potential to create a new kind of socially conscious, inspired, community-informed medical specialist is the future of medical specialty care.

Alfred Hospital leading in pharmacy services for critically unwell patients

Cristina Roman, is the Lead Pharmacist at Alfred Emergency Trauma Centre. In her 12 years working in the Emergency Department, Cristina has established pharmacy services, and filled gaps in patient care with new models of care.

One of those models of care adopted by the US and other countries, is involving pharmacists for critically unwell patients that present to the emergency department.

Australian Health Journal spoke with Cristina Roman and Lisa Bremner, Advanced Training Resident Pharmacist at Alfred Hospital Emergency Trauma Centre.

Investigating new approaches to target plaque inflammation in atherosclerosis

Associate Professor Peter Psaltis is an Academic Interventional Cardiologist who holds Level 2 NHMRC Career Development and National Heart Foundation Future Leader Fellowships. He has Faculty positions within the University of Adelaide, Central Adelaide Local Health Network (CALHN) and South Australian Health and Medical Research Institute (SAHMRI). Within SAHMRI, he is the Co-Theme Leader of the Lifelong Health, Program Leader of Heart and Vascular Health and Co-director of the Vascular Research Centre in the Lifelong Health Theme.

Cardiovascular Disease Risk Guidance and Calculator get long overdue update

Cardiovascular disease (CVD) is responsible for significant morbidity and premature mortality in Australia. Ischaemic heart disease was the leading cause of death in 2020 and cerebrovascular disease was the third most common cause of death.

As the first major update to Australian CVD risk assessment guidelines in over a decade, the 2023 Australian Guideline for assessing and managing cardiovascular disease risk  and associated Aus CVD Risk Calculator reflect the latest evidence on assessing, communicating, and managing CVD risk. Developed using Australian-specific data and the latest evidence, it supersedes the 2012 Guidelines for the management of absolute cardiovascular disease risk.

Genetic disease research imitating function and architecture of organs

Professor Wolvetang was among the first to bring the first human embryonic stem cells to Queensland, with his Wolvetang Group at the AIBN now renowned for its work with organoids: growing them, studying them, and using them to try and understand diseases and human development.

Using cutting edge technology, Professor Wolvetang designs and grows organoids both for their own work and for labs across the country, coaxing pluripotent stem cells or tissue samples into 3D structures that mimic the function and architecture of real brains, livers, kidneys, spinal cords, and intestines.

At the frontier of human cellular neuroscience research

Associate Professor Cedric Bardy is the Director of The Laboratory for Human Neurophysiology, Genetics & Stem Cells, located at SAHMRI. South Australia.

His current research uses preclinical, patient-derived cell models to test innovative therapeutic strategies, with a current focus on Parkinson’s disease, brain cancer and childhood dementia (Sanfilippo syndrome).


His work has established a platform to facilitate the discovery and validation of treatments for brain disorders. Their research is at the frontier of human cellular neuroscience research and translational applications that benefit global public health.

Junior Fellowship to develop vaccine for bacteria that cause ear infections

Dr Erin Brazel has a background in molecular and translational microbiology, with a focus on developing new ways of preventing and treating bacterial diseases. Recently Dr Brazel has been awarded a Junior Fellowship by the Passe & Williams Memorial Foundation.

The fellowship enables outstanding individuals to obtain postdoctoral training under the supervision of an experienced clinical or scientific researcher, with the view to establishing a research career in Otolaryngology, Head and Neck Surgery in Australia and/or New Zealand.

Investigating the benefits of donor human milk for preterm infants

Together, SAHMRI and Lifeblood are leading a consortium to revolutionise the way human milk, and novel products made from human milk, are used as nutritional and medical interventions to improve health outcomes in vulnerable infants, but with potential application for a diverse range of medical indications.

Currently, babies who are born early preterm – before 32 weeks – are given donor milk when their own mother’s milk is not available or in short supply. Whether donor milk is beneficial for babies born just a few weeks early is unclear, as very little research has been undertaken with these babies.

The GIFT Trial will soon commence as an investigation between SAHMRI, the University of Adelaide, the Red Cross Lifeblood Milk Bank conducted at five sites across three states in Australia.

Unleashing the potential of Paramedic skills and knowledge

According to a prominent paramedicine academic and researcher, paramedics have the potential to provide much-needed care in the community, changing the traditional healthcare model. Research points to paramedics having a wider healthcare workforce impact based on their ability to identify and fix problems 24/7.

Dr. Brendan Shannon is Head of Postgraduate Programs in the Department of Paramedicine at Monash University and a member of The Australasian College of Paramedicine. His interests including refining healthcare models, to ensure underserved communities receive requisite care. These alternative care pathways, like outreach programs, can work out of hospitals to provide care in underserved communities with social and complex chronic conditions.

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